Chercheuses et Chercheurs

Université Laval

Autre(s) lien(s)

Découvertes et identification de fractions peptidiques bioactives. Mise en évidence d’activités anticancer, antimicrobienne, antidiabète et antihypertensive de fractions peptidiques d’origine marine et végétale après le fractionnement des hydrolysats par un procédé électromembranaire.
Élaboration d’un réacteur membranaire pour la récupération de fractions bioactives. Mise au point  d’une technologie électromembranaire permettant de réaliser simultanément et en une seule étape l'hydrolyse enzymatique de la ?-lactoglobuline par la trypsine et le fractionnement des peptides anioniques et cationiques générés. La technologie s’est avérée très prometteuse en termes de taux de migration et de sélectivité peptidique.

• J. Chamberland, T. Messier, E. Dugat-Bony, M.H. Lessard, S. Labrie, A. Doyen, Y. Pouliot. (2019). Influence of feed temperature to biofouling ofultrafiltration membrane during skim milk processing. International Dairy Journal
• J. Larouche, M.H. Deschamps, L. Saucier, Y. Lebeuf, A. Doyen, G.W. Vandenberg. (2019). Effects of killing methods on lipid oxidation,colour and microbial load of black soldier fly (Hermetia illucens) larvae. Animals.
• J Bentahar, A Doyen, L Beaulieu, JS Deschênes. (2019). Acid whey permeate: An alternative growth mediumfor microalgae Tetradesmus obliquusand production of β-galactosidase. Algal Research.
• Shyam Suwal, Raquel Silveira Porto Oliveira, Mathilde Pimont-Farge, Alice Marciniak, Guillaume Brisson, Yves Pouliot, Alain Doyen. (2019). Formation of Stable Supramolecular Structure with ?-Lactoglobulin-Derived Self-Assembling Peptide f1-8 and Bovine Micellar Caseins. Journal of agricultural and food chemistry.
• Ariane Tremblay, Ronan Corcuff, Charles Goulet, Samuel Benrejeb Godefroy, Alain Doyen, Lucie Beaulieu. (2019). Valorizationof Snow Crab (Chionoecetes opilio) Cooking Effluents for Food Applications. Journal of
  the Science of Food and Agriculture.
• J. Chamberland†, D. Mercier-Bouchard, I. Dussault-Chouinard, S. Benoit, A. Doyen, M. Britten, Y. Pouliot. (2019). On the Use of Ultrafiltration or MicrofiltrationPolymeric Spiral-Wound Membranes for Cheesemilk
  Standardization: Impact onProcess Efficiency. Food.
• Franck M Perreault V Suwal S Marciniak A Bazinet L Doyen A. (2019). High hydrostatic pressure-assisted enzymatic hydrolysis improved enzymatic hydrolysis of flaxseed protein isolate andgeneration of peptides
  with antioxidant activity. Food Research International.
• S. Suwal†, J. Bentahar, A. Marciniak, L. Beaulieu, J.S. Deschênes, A. Doyen. (2019). Evidence of the production ofgalactooligosaccharide from whey permeate by the microalgae Tetradesmus obliquus. Algal
  Research.
• M. Franck, V. Perreault, S. Suwal, A. Marciniak, L. Bazinet, A. Doyen. (2019). High hydrostatic pressureassisted enzymatichydrolysis improved enzymatic hydrolysis of flaxseed protein isolate andgeneration of
  peptides with antioxidant activity. Food Research International. Food Research International.
• Alice Marciniak, Shyam Suwal, Guillaume Brisson, Michel Britten, Yves Pouliot, Alain Doyen. (2019). Evaluation of casein as a binding ligand protein for purification of alpha-lactalbumin from beta-lactoglobulin
  under high hydrostatic pressure. Food Chemistry.
• M.A. Pitino, S.M. Alashmali, K.E. Hopperton, S. Unger, Y. Pouliot, A. Doyen, D.L. O’Connor, R.P. Bazinet. (2019). Oxylipin concentration, but not fatty acidcomposition, is altered in human donor milk pasteurized
  using both thermal andnon-thermal techniques. The Bristish Journal of Nutrition.
• M.A. Pitino, S. Unger, A. Doyen, Y. Pouliot, S. Aufreiter, D. Stone, D.L.O’Connor. (2019). High hydrostatic pressure processing betterpreserves the nutrient and bioactive compound composition of human donor
  milk. The Journal of Nutrition.
• S. Suwal†, V. Perreault, A. Marciniak, E. Tamigneaux, E Deslandes, L. Bazinet, H. Jacques, L. Beaulieu, A. Doyen. (2019). Effect of High Hydrostatic Pressure andPolysaccharidases on the Extraction of Antioxidant
  Compounds from Red Seaweeds. Journal of Food Engineering.
• Boukil A, Chamberland J, Pouliot Y, Doyen A. (2018). Ultrafiltration performances and recovery ofbioactive peptides after fractionation of tryptic hydrolysate generated frompressure-treated beta-lactoglobulin. Journal
  of Membrane Science. 556: 42-53.
• Marciniak A, Naderi N, Pouliot Y, Doyen A. (2018). Enhancing production of food-derived bioactive peptides by high hydrostatic pressure technique. Trend in food science and technology. 80: 187-198.
• Pitino A. M Unger S Doyen A Pouliot Y Aufreiter S Stone D O’Connor D.L. (2018). Investigation of Alternative and Emerging Pasteurization Techniques for Human Milk Preservation. Journal of Nutrition.
• Bentahar J, Doyen A, Beaulieu L, Deschênes J-S. (2018). Investigation of ?-galactosidase production by microalgae Scenedesmus obliquus in determined growth conditions. Journal of Applied Phycology.
• Bentahar J Doyen A Beaulieu L Deschênes J-S. (2018). Acid whey permeate: an alternative growth medium for microalgae Tetradesmus obliquus and production of beta-galactosidase. Algal Research.
• Marciniak A, Suwal S, Britten M, Pouliot Y, Doyen A. (2018). Studying a chaperone-like effect of betacasein on pressure-induced aggregation of beta-lactoglobulin in the presence ofalpha-lactalbumin. Food
  Hydrocolloïds. 84: 9-15.
• Marciniak A, Suwal S, Britten M, Pouliot Y, Doyen A. (2018). Studying a chaperone-like effect of betacasein on pressure-induced aggregation of beta-lactoglobulin in the presence ofalpha-lactalbumin. Food
  Hydrocolloïds. 84: 9-15.
• Paredes-Valencia A Doyen A Benoit S Margni M Pouliot Y. (2018). Effect of Ultrafiltration of Milk Prior to Fermentation on Mass Balance and Process Efficiency in Greek-Style YogurtManufacture. Foods.
• N. Naderi, J. D. House, Y. Pouliot, A. Doyen. (2017). Effect of freezing, thermal pasteurization, and hydrostatic pressure on fractionation and folate recovery in egg yolk. Journal of Agricultural and Food
  Chemistry. 65: 7774-7780.
• J. Chamberland, M-H. Lessard, S. Labrie, L. Bazinet, A. Doyen, Y. Pouliot. (2017). Biofouling of ultrafiltration membrane by dairy fluids: Characterization of pioneer colonizer bacteria using a
  DNAmetabarcoding approach. Dairy Science and Technology. 96: 827-843.
• M. Persico, S. Mikhaylin, A. Doyen, L. Firdaous, M. Chevalier, C. Flahaut, P. Dhulster, L. Bazinet. (2017). Formation of peptide layers and adsorption mechanisms on a negatively charged membrane surface.
  Journal of Colloid & Interface Science. 508: 488-499.
• Suwal S, Rozoy E, Manenda M, Doyen A, Bazinet L. (2017). Comparative study of in situ and ex situ enzymatic hydrolysis of milk protein and separation of bioactive peptides in anelectromembrane reactor.
  ACS Sustainable Chemistry & Engineering. 5: 5330-5340.
• N. Naderi, J. D. House, Y. Pouliot, A. Doyen. (2017). Effects of High Hydrostatic Pressure Processing on Hen Egg Compounds and Egg Products. Comprehensive Reviews in Food Science and Food Safety. 16:
  707-720.
• M. Persico, S. Mikhaylin, A. Doyen, L. Firdaous, V. Nikonenko, N. Pismenskaya, L. Bazinet. (2017). Prevention of peptide fouling on ion-exchange membranes during electrodialysis in overlimiting conditions.
  Journal of Membrane Science. 543: 212-221.
• Perreault V, Hénaux L, Bazinet L, Doyen A. (2017). Pretreatment of flaxseed protein isolate with high hydrostatic pressure: impacts on protein structure, enzymatic hydrolysis and final hydrolysate
  antioxidant properties. Food Chemistry. 221: 1805-1812.
• J. Chamberland, G. Beaulieu-Carbonneau, M-H. Lessard, S. Labrie, L. Bazinet, A. Doyen, Y. Pouliot. (2017). Effect of membrane material chemistry and properties on biofouling susceptibility during milk and
  cheese whey ultrafiltration. Journal of Membrane Science. 542: 208-216.
• N. Naderi, A. Doyen, J. D. House, Y. Pouliot. (2017). The use of high hydrostatic pressure to generatefolate-enriched extracts from the granule fraction of hen's egg yolk. Food Chemistry. 232: 253-262.
• Chamberland J, Lessard M-H, Labrie S, Bazinet L, Doyen, A, Pouliot, Y. (2017). A sequencing approach targeting the 16S rRNA gene unravels the biofilm composition of spiral-wound membranes used in the
  dairy industry. Dairy Science and Technology. 96: 827-843.
• N. Naderi, J. D. House, Y. Pouliot, A. Doyen. (2017). High hydrostatic pressure effect in extraction of 5-methyltetrahydrofolate (5-MTHF) from egg yolk and granule fractions. Innovative Food Science and
  Emerging Technologies. 43: 191-200.
• M. Leu, A. Marciniak, J. Chamberland, L. Bazinet, Y. Pouliot. (2017). Effect of skim milk treated with high hydrostatic pressure on permeate flux and fouling during ultrafiltration. Journal of Dairy Science. 100:
  7071-7082.
• Tremblay-Marchand D, Doyen A, Britten M, Pouliot Y. (2016). A process efficiency assessment of serum protein removal from milk using ceramic graded permeability microfiltration membrane. Journal of Dairy
  Science. 99(7): 5230-5243.
• Methot-Hains, S., Benoit,S., Bouchard, C, Doyen, A., Bazinet, L., Pouliot, Y. (2016). Effect of transmembrane pressure control on energy efficiency during skim milk concentration by ultrafiltration at 10
  and 50°C. Journal of Dairy Science. 99: 8655-8664.
• M. Persico, S. Mikhaylin, A. Doyen, L. Firdaous, R. Hammami, L. Bazinet. (2016). How peptide physicochemical and structural characteristics affect anion-exchange membranes fouling by a tryptic
  whey protein hydrolysate. Journal of Membrane Science. 221: 1805-1812.
• Suwal S, Doyen A, Bazinet L. (2015). Characterization of protein, peptide and amino acid fouling on ion-exchange and filtration membranes: review of current and recently developed methods. Journal of
  Membrane Sciens. 496: 267-283.
• Chevrier G, Mitchell PL, Rioux LE, Hasan F, Jin T, Roblet C, Doyen A, Pilon G, St-Pierre P, Lavigne C, Bazinet L, Jacques H, Gill T, McLeod RS, Marette A. (2015). Low-Molecular-Weight Peptides from Salmon Protein Prevent Obesity-Linked Glucose Intolerance, Inflammation and Dyslipidemia in LDLR-/-/ ApoB100/100 Mice. The Journal of Nutrition. 145(7): 1415-1422.
• Bazinet L, Doyen A. (2015). Antioxidants, Mechanisms, and Recovery by Membrane Processes. Critical Reviews in Food Sciences and Nutrition. 57(4): 677-700.
• Doyen, A.; Udenigwe, C.C.; Mitchell, P.; Marette, A.; Aluko, R.E.; Bazinet, L. Respective anti-diabetic and antihypertensive activities of two flaxseed protein hydrolysate fractions revealed following their simultaneous separation by electrodialysis with ultrafiltration membranes. Food Chemistry, 145 (1), 66-76.
• Doyen, A.; Husson, E; Bazinet, L. (2013) Use of an electrodialytic reactor for the simultaneous ?-lactoglobulin enzymatic hydrolysis and fractionation of generated bioactive peptides. Food Chemistry, 136 (3-4), 1193-1202.
• Doyen, A.; Roblet, C.; Beaulieu, L.; Saucier, L.; Pouliot, Y.; Bazinet, L. (2012). Electroseparation of antimicrobial peptides from snow crab by-product hydrolysate by electrodialysis with ultrafiltration membranes. Food Chemistry 132 (3), 1177-1184.
• Doyen, A.; Beaulieu, L.; Saucier, L.; Pouliot, Y.; Bazinet, L. (2011) Demonstration of in vitro anticancer properties of peptide fractions from a snow crab by-products hydrolysate after separation by electrodialysis with ultrafiltration membranes. Separation and Purification Technology 78, (3), 321-329.
• Doyen, A.; Beaulieu, L.; Saucier, L.; Pouliot, Y.; Bazinet, L. (2011) Impact of Ultrafiltration Membrane Material on Peptide Separation from a Snow Crab Byproduct Hydrolysate by Electrodialysis with Ultrafiltration Membranes. Journal of Agricultural and Food Chemistry 59 (5), 1784-1792.